Tuesday, October 15, 2013

6 Photos Of The Government Shutdown

What happens when the United States is closed? We asked you to show us—to capture both areas shut down by the government and just random things you found abandoned, rusted, and closed. And from here, the US looks like a post-apocalyptic wasteland.

Read more...


    






Source: http://feeds.gawker.com/~r/gizmodo/full/~3/9isNVt7O1DA/6-photos-of-the-government-shutdown-1445514834
Tags: Heartbreaker Justin Bieber   Witches of East End   Becky G   Kidd Kraddick   Ultron  

Before Church Songbooks There Was 'Lined-Out' Singing


Hidden deep in the hills of Appalachia, there's a tradition of gospel singing that has not changed in 300 years. "Lined-out" singing is still practiced by congregations of the Old Regular Baptist Church. The song leader calls out a line and the people respond in a mournful, soaring chorus.


Source: http://www.npr.org/2013/10/15/234606252/before-church-songbooks-there-was-lined-out-singing?ft=1&f=1016
Similar Articles: drew brees   downton abbey   Chobani Recall   school shooting   paulina gretzky  

The role of 'master regulators' in gene mutations and disease

The role of 'master regulators' in gene mutations and disease


[ Back to EurekAlert! ]
Public release date: 13-Oct-2013
[


| E-mail



| Share Share

]

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego



Researchers identify key proteins that help establish cell function



Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and off.


Writing in the October 13, 2013 Advance Online Publication of Nature, the scientists say their approach could make it quicker and easier to identify specific gene mutations associated with increased disease risk an essential step toward developing future targeted treatments, preventions and cures for conditions ranging from diabetes to neurodegenerative disease.


"Given the emerging ability to sequence the genomes of individual patients, a major goal is to be able to interpret that DNA sequence with respect to disease risk. What diseases is a person genetically predisposed to?" said principal investigator Christopher Glass, MD, PhD, a professor in the departments of Medicine and Cellular and Molecular Medicine at UC San Diego.


"Mutations that occur in protein-coding regions of the genome are relatively straight forward, but most mutations associated with disease risk actually occur in regions of the genome that do not code for proteins," said Glass. "A central challenge has been developing a strategy that assesses the potential functional impact of these non-coding mutations. This paper lays the foundation for doing so by examining how natural genetic variation alters the function of genomic regions controlling gene expression in a cell specific-manner."


Cells use hundreds of different proteins called transcription factors to "read" the genome, employing those instructions to turn genes on and off. These factors tend to be bound close together on the genome, forming functional units called "enhancers." Glass and colleagues hypothesized that while each cell has tens of thousands of enhancers consisting of myriad combinations of factors, most enhancers are established by just a handful of special transcription factors called "master regulators." These master regulators play crucial, even disproportional, roles in defining each cell's identity and function, such as whether it will be a muscle, skin or heart cell.


"Our main idea was that the binding of these master regulators is necessary for the co-binding of the other transcription factors that together enable enhancers to regulate the expression of nearby genes," Glass said.


The scientists tested and validated their hypothesis by looking at the effects of approximately 4 million DNA sequence differences affecting master regulators in macrophage cells in two strains of mice. Macrophages are a type of immune response cell. They found that DNA sequence mutations deciphered by master regulators not only affected how they bound to the genome, but also impacted neighboring transcription factors needed to make functional enhancers.


The findings have practical importance for scientists and doctors investigating the genetic underpinnings of disease, said Glass. "Without actual knowledge of where the master regulator binds, there is relatively little predictive value of the DNA sequence for non-coding variants. Our work shows that by collecting a focused set of data for the master regulators of a particular cell type, one can greatly reduce the 'search space' of the genome in a particular cell type that would be susceptible to the effects of mutations. This allows prioritization of mutations for subsequent analysis, which can lead to new discoveries and real-world benefits."

###

Co-authors include Sven Heinz, Casey Romanoski, Karmel A. Allison, Department of Cellular and Molecular Medicine, UCSD; Christopher Benner, Department of Cellular and Molecular Medicine, UCSD, Salk Institute for Biological Studies and San Diego Center for Systems Biology; Minna U. Kiakkonen, Department of Cellular and Molecular Medicine, UCSD and University of Eastern Finland and Luz D. Orozco, UCLA.


Funding support came from National Institutes of Health grants DK091183, CA17390 and DK063491, a Foundation Leducq Career Development award, the Academy of Finland, Finnish Foundation for Cardiovascular Research, Finnish Cultural Foundation, North Savo Regional Fund and the American Heart Association.



[ Back to EurekAlert! ]

[


| E-mail



| Share Share

]

 


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.




The role of 'master regulators' in gene mutations and disease


[ Back to EurekAlert! ]
Public release date: 13-Oct-2013
[


| E-mail



| Share Share

]

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego



Researchers identify key proteins that help establish cell function



Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and off.


Writing in the October 13, 2013 Advance Online Publication of Nature, the scientists say their approach could make it quicker and easier to identify specific gene mutations associated with increased disease risk an essential step toward developing future targeted treatments, preventions and cures for conditions ranging from diabetes to neurodegenerative disease.


"Given the emerging ability to sequence the genomes of individual patients, a major goal is to be able to interpret that DNA sequence with respect to disease risk. What diseases is a person genetically predisposed to?" said principal investigator Christopher Glass, MD, PhD, a professor in the departments of Medicine and Cellular and Molecular Medicine at UC San Diego.


"Mutations that occur in protein-coding regions of the genome are relatively straight forward, but most mutations associated with disease risk actually occur in regions of the genome that do not code for proteins," said Glass. "A central challenge has been developing a strategy that assesses the potential functional impact of these non-coding mutations. This paper lays the foundation for doing so by examining how natural genetic variation alters the function of genomic regions controlling gene expression in a cell specific-manner."


Cells use hundreds of different proteins called transcription factors to "read" the genome, employing those instructions to turn genes on and off. These factors tend to be bound close together on the genome, forming functional units called "enhancers." Glass and colleagues hypothesized that while each cell has tens of thousands of enhancers consisting of myriad combinations of factors, most enhancers are established by just a handful of special transcription factors called "master regulators." These master regulators play crucial, even disproportional, roles in defining each cell's identity and function, such as whether it will be a muscle, skin or heart cell.


"Our main idea was that the binding of these master regulators is necessary for the co-binding of the other transcription factors that together enable enhancers to regulate the expression of nearby genes," Glass said.


The scientists tested and validated their hypothesis by looking at the effects of approximately 4 million DNA sequence differences affecting master regulators in macrophage cells in two strains of mice. Macrophages are a type of immune response cell. They found that DNA sequence mutations deciphered by master regulators not only affected how they bound to the genome, but also impacted neighboring transcription factors needed to make functional enhancers.


The findings have practical importance for scientists and doctors investigating the genetic underpinnings of disease, said Glass. "Without actual knowledge of where the master regulator binds, there is relatively little predictive value of the DNA sequence for non-coding variants. Our work shows that by collecting a focused set of data for the master regulators of a particular cell type, one can greatly reduce the 'search space' of the genome in a particular cell type that would be susceptible to the effects of mutations. This allows prioritization of mutations for subsequent analysis, which can lead to new discoveries and real-world benefits."

###

Co-authors include Sven Heinz, Casey Romanoski, Karmel A. Allison, Department of Cellular and Molecular Medicine, UCSD; Christopher Benner, Department of Cellular and Molecular Medicine, UCSD, Salk Institute for Biological Studies and San Diego Center for Systems Biology; Minna U. Kiakkonen, Department of Cellular and Molecular Medicine, UCSD and University of Eastern Finland and Luz D. Orozco, UCLA.


Funding support came from National Institutes of Health grants DK091183, CA17390 and DK063491, a Foundation Leducq Career Development award, the Academy of Finland, Finnish Foundation for Cardiovascular Research, Finnish Cultural Foundation, North Savo Regional Fund and the American Heart Association.



[ Back to EurekAlert! ]

[


| E-mail



| Share Share

]

 


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.




Source: http://www.eurekalert.org/pub_releases/2013-10/uoc--tro101013.php
Similar Articles: breast cancer awareness   downton abbey   Sunny Ozell   Disney Infinity   Maria Mitchell  

this week's independent wrestling calendar - 1Wrestling.com - Pro ...

Posted October 14th, 2013 by 1Wrestling News Team





** Below is a listing of independent wrestling events for the next two weeks. This listing is sent weekly.
** Please send any events you would like added to nate_stein@hotmail.com or on Twitter @PSPhenom.


Wed, Oct 16 – RPW – 1106 E. Third ST, Dayton, OH – 7 pm – Facebook.com/RockstarProWrestling
Wed, Oct 16 – Ohio Valley Wrestling – Davis Arena, 4400 Shepherdsville RD, Louisville, KY – 6:30 pm – OVWrestling.com


Thu, Oct 17 – HKW – 9505 Dennison Ave, Cleveland, OH – 7 pm- facebook.com/hardknockwrestling


Fri, Oct 18 – New Japan/NWA Houston – Humble Civic Center, Humble, TX – 7:30 pm – Facebook.com/nwahouston
Fri, Oct 18 – Premiere Wrestling Xperience – Tremont Music Hall, 400 W Tremont Ave, Charlotte, NC – 7 pm – PWXProWrestling.com
Fri, Oct 18 – 1CW – 6972 Dixie Highway, Franklin, OH – 7 pm – Facebook.com/groups/183747681655800/420820161281883/
Fri, Oct 18 – NWA SAW – 1214B Louisville Hwy, Millersville, TN – 7:30 pm
Fri, Oct 18 – PWE – The Giant Flea Market, 1700 W Realfoot Ave, Union City, TN – 8 pm – facebook.com/ProWrestlingElitePresentsAllActionWrestling
Fri, Oct 18 – Real Pro Wrestling Federation – Big Wheel Roller Skating Center, 3226 N 5th ST, East Stroudsburg, PA – 7:30 pm – Facebook.com/RealProWrestlingFederation
Fri, Oct 18 – Main Event Wrestling – VFW Building, 2566 Morrison ST, Gallatin, TN – 8 pm
Fri, Oct 18 – 3XW – Baratta’s Forte Center, 615 3rd ST, Des Moines, Iowa – 7:30 pm – facebook.com/3XWrestling
Fri, Oct 18 – Pro Wrestling Epic – Logan County Fairgrounds, Lincoln, IL – 7:30 pm – ProWrestlingEpic.net
Fri, Oct 18 – NWA Wrestling Revolution – El Rey Theatre, 311 S 17th ST, McAllen, TX – 8 pm – facebook.com/wrtexas
Fri, Oct 18 – River City Wrestling – Sideliners Grill, 15630 Henderson Pass, San Antonio, TX – RCW-Wrestling.com
Fri, Oct 18 – Manor Pro Wrestling – Osceola Heritage Park, 1875 Silver Spur Lane, Kissimmee, FL – ManorProWrestling.com
Fri, Oct 18 – ICW – The Elks Lodge, Queens Blvd, Elmhurst, Queens, NY – 8 pm
Fri, Oct 18 – East Coast Professional Wrestling – Paramus Elk’s Lodge, 210 Route 17 N, Paramus, NJ – 7:30 pm – ECPW1.com
Fri, Oct 18 – Pro Wrestling Academy – St. Sebastian Club, 86 Father Salemi DR, Ansonia, CT – 8 pm – Facebook.com/PWACT
Fri, Oct 18 – Metro Pro Wrestling – Rookies Bar & Grill, 1519 Oak ST, Wyandotte, MI – 7:30 pm


Sat, Oct 19 – AIWF Mid-Atlantic – National Guard Armory, 185 Patrol Station RD, Mt. Airy, NC – 7:30 pm – aiwf.net
Sat, Oct 19 – AIWF C4W – Sports Mall (Formerly X Complex), Myrtle Beach, SC – 8 pm
Sat, Oct 19 – AIWF ICW – Boys & Girls Club, Louisburg, NC – 7:30 pm
Sat, Oct 19 – AIWF UPWA – Legion Hall, Mullens, WV – 7:30 pm – facebook.com/upwawrestling
Sat, Oct 19 – New Japan/BOW – Woodlawn Gym, 1103 Cincinnati 78201, San Antonio, TX – facebook.com/BrandedOutlawEnt
Sat, Oct 19 – SHOW – 6972 South Dixie Hwy, Franklin, OH – 3 pm – facebook.com/SuperHeroesOfWrestlingShow
Sat, Oct 19 – Magnum Pro – G.O. Ministries, 3703 Station Ave, Ashtabula, OH – 5 pm – MagnumProWrestling.com
Sat, Oct 19 – SICW – East Carondelet Community Center, East Carondelet, IL – 8 pm – saintlouiswrestling.com
Sat, Oct 19 – PWX – 2125 Beacon ST, McKeesport, PA – 7:30 pm – prowrestlingexpress.com
Sat, Oct 19 – OTW – 1041 Glassboro Rd, Williamstown, NJ – 2 pm – OldTimeWrestling.net
Sat, Oct 19 – TAP – Old Cheese Factory, 191 Industrial DR, McMinnville, TN – 8 pm – facebook.com/TAPWrestling1
Sat, Oct 19 – XWE – Hocking College Student Center, 3301 Hocking Pkwy Dr, Nelsonville, OH – 8 pm – Facebook.com/XWEwrestling
Sat, Oct 19 – IZW – Impact Arena, 1009 SW F Ave, Lawton, OK – 7 pm – IZWrestling.com
Sat, Oct 19 – PWS – 2229 Charles Town RD, Martinsburg, WV – facebook.com/ProWrestlingShowcase
Sat, Oct 19 – Wildcat Championship Wrestling – 101 Hilltop DR, Lawrenceburg, KY – 7:30 pm – facebook.com/pages/The-Real-Wildcat-Championship-Wrestling-WCCW/307961922578873
Sat, Oct 19 – DCW – Farmington Fire Department, Farmington, DE – Facebook.com/DCWPROWRESTLING
Sat, Oct 19 – NYWC – 435 Brook Ave Unit 13, Deer Park, NY – NYWCwrestling.com
Sat, Oct 19 – IWC – Court Time Sports Center, 95 Enterprise ST, Suite 100, Elizabeth, PA – 8 pm – IWCwrestling.com
Sat, Oct 19 – Platinum Championship Wrestling – 2001 Main ST, Porterdale, GA – 6 pm – Facebook.com/platinumchampionshipwrestling
Sat, Oct 19 – Apex & Vendetta – Pappy Pineda Promotions, 7962 Salt Lake Ave, Huntington Park, CA – 6 pm – facebook.com/TheApexPro
Sat, Oct 19 – MPW – 2850 Lemon DR, Simi Valley, CA – MPWLive.com
Sat, Oct 19 – Uproar – Verizon Event Center, 8718 Trouble Creek RD, New Port Richey, FL – 7 pm – uproarwrestling.com
Sat, Oct 19 – NEFW – Boys & Girls Club of Chicopee, 580 Meadow ST, Chicopee, MA – 7 pm – nefwprowrestling.com
Sat, Oct 19 – Canadian All Pro Wrestling – Royal Canadian Legion Branch #1, 116 7 Ave SE, Calgary, AB – canadianallpro.com
Sat, Oct 19 – TCW – The Orange Peel, 101 Biltmore Ave, Asheville, NC – 7 pm
Sat, Oct 19 – Border City Wrestling – St. Clair College, 2000 Talbot RD W, Windsor, ON – 7:30 pm – facebook.com/bordercitywrestling
Sat, Oct 19 – HeART of Lucha – Centro Cultural De La Raza, 2004 Park Blvd., San Diego, CA – 5 pm
Sat, Oct 19 – Magnum Pro – Eagles Club, 1530 Ave F, Council Bluffs, IA
Sat, Oct 19 – Ultimate Championship Wrestling – Hardin Community Center, Hardin, KY – 7:30 pm
Sat, Oct 19 – Northern Wrestling Federation – Richwood Event Center, Walton, KY – 8 pm
Sat, Oct 19 – Kentucky Zone Wrestling – Ferguson Gym, Somerset, KY – 7:30 pm
Sat, Oct 19 – World Wrestling Alliance – Central City Convention Center, Central City, KY
Sat, Oct 19 – NWA Top of Texas – 2650 Dumas DR, Amarillo, TX – 7:30 pm – https://www.facebook.com/NWA.TOPOFTEXAS
Sat, Oct 19 – Tennessee All-Pro Wrestling – Old Cheese Factory, 191 Industrial DR, McMinnville, TN – 8 pm – facebook.com/TAPWrestling1
Sat, Oct 19 – Bare Knuckles Pro Wrestling – Niagara Centre for the Arts, 4700 Epworth Circle, Niagara Falls, ON – 6:30 pm – bkpwrestling.com
Sat, Oct 19 – Pro Wrestling Guerrilla – American Legion Post #308, 7338 Canby Ave., Reseda, CA 91335 – 8 PM – prowrestlingguerrilla.com
Sat, Oct 19 – PPW – Strand Roller Rink, 110 W Blaine ST, McAdoo, PA – 7 pm
Sat, Oct 19 – Pure Pro Wrestling – Pelham Community Center, Pelham, NC – 7:30 pm – facebook.com/pureprowrestling
Sat, Oct 19 – Pro Wrestling Battleground – Wilebski’s Legendary Blues Saloon, 1638 Rice ST, St. Paul, MN – 6 pm – facebook.com/ProWrestlingBattleground
Sat, Oct 19 – Pure Wrestling Association – Navy League Hall, 911 13th Ave, Campbell River, BC – 7:40 pm – facebook.com/pwacanadawrestling
Sat, Oct 19 – AIWF Texas TCW – Killeen Community Center, 2201 E. Veterans Memorial Blvd, Killeen, TX – 6:30 pm – tcw-austin.com
Sat, Oct 19 – Pennsylvania Premiere Wrestling – Strand Roller Rink, McAdoos, PA – PennsylvaniaPW.weebly.com
Sat, Oct 19 – XWA – West Wawick Civic Center, 100 Factory ST, West Warick, RI – 7 pm – facebook.com/XWARI
Sat, Oct 19 – Jersey Championship Wrestling – Ultimate Sports America, 12 Wright Way, Oakland, NJ – 7:30 pm – JerseyChampionshipWrestling.com
Sat, Oct 19 – Border City Wrestling – St. Clair College, 2000 Talbot RD W, Windsor, N – 7:30 pm – facebook.com/bordercitywrestling
Sat, Oct 19 – Midwest Pro Wrestling – Monroe Fraternal Order of Police Hall, 1051 Strasburg RD, Monroe, MI – 7 pm – MPWAwrestling.com
Sat, Oct 19 – Metro Pro Wrestling – Rookie’s Sports Pub, 1519 Oak, Wyandotte, MI – 7:30 pm
Sat, Oct 19 – East Coast Professional Wrestling – Herkimer County Fairgrounds, 133 Cemetary ST, Frankfort, NY – 7:30 pm – ECPW1.com
Sat, Oct 19 – New Era – Shelbyville Boys Club, Shelbyville, IN – 7 pm – newerawrestling.net
Sat, Oct 19 – MXCW – 280 Bridge ST, Springfield, MA – 3 pm
Sat, Oct 19 – Valour Pro Wrestling – Leo Independent Fire Engine Co. No. 1, 201 W Broadway, Red Lion, PA – 6 pm
Sat, Oct 19 – Porkchop fundraiser – Brock Gym, 622 N Main ST, Mocksville, NC – 8 pm – facebook.com/PleaseHelpPorkchop


Sun, Oct 20 – Anarchy Championshipo Wrestling – Mohawk, 912 Red River, Austin, TX – 5:25 pm – anarchychampionshipwrestling.com
Sun, Oct 20 – I Believe In Wrestling – Team Vision Dojo, 6923 Narcoossee RD, #620, Orlando, FL – 5 pm – ibelieveinwrestling.com
Sun, Oct 20 – KAPOW – Progress Hall, SE9 1SL, London, UK – 2:30 pm – Facebook.com/events/33845288962092
Sun, Oct 20 – Rampage Pro – Johnny G’s Fun Center, 815 Russell Pkwy, Warner Robbins, GA – 3 pm – RampageProWrestling.net
Sun, Oct 20 – Prime – Ohio Nets Sports Complex, 12665 Corporate DR, Parma, OH – 3 pm – primewrestling.com
Sun, Oct 20 – Heartland Wrestling Association – LSC Arena, 555 N Verity Pkwy, Middletown, OH – 5 pm – Facebook.com/HWAOnline
Sun, Oct 20 – Alpha-1 – Knights of Columbus Hall, 222 Queenston RD, Hamilton, ON – 6 pm – alpha-1wrestling.com
Sun, Oct 20 – UWA – Jammerz Rollerdome, 1515 Lynch Lane, Clarksville, IN – 7 pm
Sun, Oct 20 – Aztec Pro Wrestling – Yost Theater, 307 N Spurgeon ST, Santa Ana, CA – 3 pm
Sun, Oct 20 – Lucha Libre Masked Warriors – Fairplex, 1101 W McKinley Ave, Pomona, CA – 8 pm – GreatAmericanNightmare.com
Sun, Oct 20 – Ohio Valley Wrestling – Derby Park Expo, Lousivlle, KY – 6 pm
Sun, Oct 20 – Michigan Wrestling Organization – City Market, 3600 S Dort Hwy, Flint, MI – 2 pm – MWOonline.net
Sun, Oct 20 – UWA – ?, Clarksville, IN – 6:30 pm – facebook.com/wrestlinguwa
Sun, Oct 20 – 3AW – Odas Park Orillia, 4500 Fairgrounds RD, RR #2, Orillia, ON – 3 pm – 3AWrestling.com
Sun, Oct 20 – Pier Six Wrestling – Hamlin Sportatorium, 53 King ST, Hamlin, NY – 4 pm – facebook.com/pier6wrestling
Sun, Oct 20 – Supreme Pro Wrestling – 6200 McMahon Dr, Sacramento, CA – 4:30 pm – facebook.com/supremeprowrestling


Wed, Oct 23 – RPW – 1106 E. Third ST, Dayton, OH – 7 pm – Facebook.com/RockstarProWrestling
Wed, Oct 23 – Ohio Valley Wrestling – Davis Arena, 4400 Shepherdsville RD, Louisville, KY – 6:30 pm – OVWrestling.com


Thu, Oct 24 – HKW – 9505 Dennison Ave, Cleveland, OH – 7 pm- facebook.com/hardknockwrestling
Thu, Oct 24 – Pro Wrestling Battle Arts – Polish Alliance Hall, 219 Olive Ave, Oshawa, ON
Thu, Oct 24 – Slam U – Arizona Event Center, 1300 S Country Club DR, Mesa, AZ – Facebook.com/SlamUWrestling


Fri, Oct 25 – 1CW – 6972 Dixie Highway, Franklin, OH – 7 pm – Facebook.com/groups/183747681655800/420820161281883/
Fri, Oct 25 – NWA SAW – 1214B Louisville Hwy, Millersville, TN – 7:30 pm
Fri, Oct 25 – PWE – The Giant Flea Market, 1700 W Realfoot Ave, Union City, TN – 8 pm – facebook.com/ProWrestlingElitePresentsAllActionWrestling
Fri, Oct 25 – Main Event Wrestling – Bangor Parks & Recreation Center, 647 Main ST, Bangor, ME – 7:30 pm – Facebook.com/mewrestling.promotions
Fri, Oct 25 – Main Event Wrestling – VFW Building, 2566 Morrison ST, Gallatin, TN – 8 pm
Fri, Oct 25 – Ohio Valley Wrestling – Simmons Middle School, Fleminsburg, KY – 8 pm – OVWrestling.com
Fri, Oct 25 – NWA Wrestling Revolution – El Rey Theatre, 311 S 17th ST, McAllen, TX – 8 pm – facebook.com/wrtexas
Fri, Oct 25 – DOA – Keizer Lions Club, 4100 Cherry Ave NE, OR – 7:30 pm – facebook.com/DOAProWrestling
Fri, Oct 25 – World of Hurt Wrestling – Whitehall Athletic Club, 62 Poultnet ST, Whitehall, NY – 7 pm – Facebook.com/wohwrestling
Fri, Oct 25 – Northeast Championship Wrestling – Elks Home of Norwood, 152 Winslow Ave, Norwood, MA – 7 pm – thencw.com
Fri, Oct 25 – Brew City Wrestling – Knights of Columbus, 1800 S 92nd ST, West Allis, WI – 7:30 pm – brewcitywrestling1.com
Fri, Oct 25 – Smash Wrestling- Inukshuk High School Gymnasium, 501 Ring RD, Iqaluit, ON – 6:30 pm – Smash-Wrestling.com


Sat, Oct 26 – CTWE – Bethany Town Hall, Bethany, CT – ctweprowrestling.com
Sat, Oct 26 – OTW – 1041 Glassboro Rd, Williamstown, NJ – 2 pm – OldTimeWrestling.net
Sat, Oct 26 – TAP – Old Cheese Factory, 191 Industrial DR, McMinnville, TN – 8 pm – facebook.com/TAPWrestling1
Sat, Oct 26 – IZW – Impact Arena, 1009 SW F Ave, Lawton, OK – 7 pm – IZWrestling.com
Sat, Oct 26 – UIW – ? – Facebook.com/events/476526355775735/
Sat, Oct 26 – Zero 1 USA – Fluid Event Center, 601 N Country Fair DR, Champaign, IL – 6 pm – facebook.com/zero1supreme
Sat, Oct 26 – Wildcat Championship Wrestling – 101 Hilltop DR, Lawrenceburg, KY – 7:30 pm – facebook.com/pages/The-Real-Wildcat-Championship-Wrestling-WCCW/307961922578873
Sat, Oct 26 – LICW/NCWA/EWA – Edgecombe County Courthouse, Tarboro, NC – Facebook.com/LeagueOfIntegrityChampionshipWrestlingLoi
Sat, Oct 26 – Northeast Wrestling – Bethany Town Hall, Bethany, CT – Northeastwrestling.com
Sat, Oct 26 – Anarchy – 4236 Level Grove RD, Cornelia, GA – Anarchy-Wrestling.net
Sat, Oct 26 – Ring of Honor – Frontier Fieldhouse, Chicago Ridge, IL – 7:30 pm – ROHwrestling.com
Sat, Oct 26 – Extreme American Wrestling – Royal British Legion Club, 210 Broadway, Yaxley, Peterborough Cambs, UK – 7 pm – eawrestling.co.uk
Sat, Oct 26 – Zero 1 – Fluid Event Center, 601 N Country Fair DR, Champaign, IL – 6 pm- facebook.com/zero1supreme
Sat, Oct 26 – Pro Wrestling Kingdom – The Crescent, Sheepcote Street, Birmingham, UK – 6 pm – facebook.com/PWKingdom
Sat, Oct 26 – Funkdafied Wrestling – Long Hill Community Center, Sterling, NJ – FunkdafiedWrestling.com
Sat, Oct 26 – Knokx Pro – The Domain, 11108 Tuxford ST, Sun Valley, CA – 7 pm – KnokxPro.com
Sat, Oct 26 – NWA Central States – Knights of Columbus, 100 E 5th ST, Cahokia, IL
Sat, Oct 26 – Ohio Valley Wrestling – St. Rita Gym, Louisville, KY – 7:30 pm – OVWrestling.com
Sat, Oct 26 – Southern Wrestling Entertainment – EW Arena, Hillview, KY – 7 pm
Sat, Oct 26 – Traditional Southern Wrestling – National Guard Armory, London, KY – 7 pm
Sat, Oct 26 – Prime Time Wrestling – Mackville Community Center, Mackville, KY – 8 pm
Sat, Oct 26 – NWA Top of Texas – 2650 Dumas DR, Amarillo, TX – 7:30 pm – https://www.facebook.com/NWA.TOPOFTEXAS
Sat, Oct 26 – Tennessee All-Pro Wrestling – Old Cheese Factory, 191 Industrial DR, McMinnville, TN – 8 pm – facebook.com/TAPWrestling1
Sat, Oct 26 – Knights of the Squared Circle – River Ridge High School, New Port Richey, FL – 7 pm – facebook.com/acwpasco
Sat, Oct 26 – NWA Power Slam Entertainment – Knights of Columbus, 100 E Fifth ST, Cahokia, IL – 7 pm – NWA-CCW.com
Sat, Oct 26 – Phoenix Pro – Backyard Event Center, 6740 Old US 22, New Florence, PA – 7 pm – PhoenixProWrestling.com
Sat, Oct 26 – Real Warrior Entertainment – Nomads Adventure Quest, 100 Bidwell RD, South Windsor, CT – 7:30 pm – Facebook.com/RingWarriorEntertainment
Sat, Oct 26 – Ground Xero Wrestling – JEJ Moore Middle School, 11455 Prince George DR, Prince George, VA – 6 pm – GoGXW.com
Sat, Oct 26 – AIWF Texas TCW – Dove Springs Rec Center, 5801 Ainez DR, Austin, TX – 6:30 pm – tcw-austin.com
Sat, Oct 26 – United States Wrestling Alliance – Maxwell Snyder Armory, 9900 Normandy Blvd, Jacksonville, FL – 7 pm – USWrestlingAlliance.com
Sat, Oct 26 – Smash Wrestling- Inukshuk High School Gymnasium, 501 Ring RD, Iqaluit, ON – 6:30 pm – Smash-Wrestling.com
Sat, Oct 26 – East Coast Professional Wrestling – Our Lady of Guadalupe School, 1514 72nd ST, Brooklyn, NY – 7:30 pm – ECPW1.com
Sat, Oct 26 – Anarchy Wrestling – Anarchy Arena, 4236 Level Grove RD, Cornelia, GA – 8 pm – anarchy-wrestling.net


Sun, Oct 27 – Wrestling Is Cool – 1030 Delsea DR, Bldg 4W, Deptford, NJ – 3 pm – WrestlingIsCool.com
Sun, Oct 27 – Southside Wrestling Entertainment – The Priory Centre, Priory Lane, Saint Neots, UK – 5:30 pm – facebook.com/NBWSouthside
Sun, Oct 27 – UWA Elite – SMG Sportsplex, 215 Durham Ave, Metuchen, NJ – 11 am – UWAElite.com
Sun, Oct 27 – UWA Elite – SMG Sportsplex, 215 Durham Ave, Metuchen, NJ – 1:30 pm – UWAElite.com
Sun, Oct 27 – DOA – East Portland Moose Lodge, 16411 NE Halset ST, Portland, OR – 7:30 pm – facebook.com/DOAProWrestling




Source: http://www.1wrestling.com/2013/10/14/this-weeks-independent-wrestling-calendar-3/
Tags: sofia vergara   Nfl Fantasy   made in america  

Monday, October 14, 2013

Michael Douglas: I lied about my type of cancer

Celebs











3 hours ago

Michael Douglas went public with his cancer diagnosis, but the actor told Samuel L. Jackson on British talk show "This Morning" that he wasn't quite honest about the disease.

Douglas had a tumor at the base of his tongue, although for nine months doctors kept telling him it was only an infection and giving him antibiotics. When he was finally properly diagnosed his doctor suggested he tell people he had throat cancer, not tongue cancer.

"If we do have to do surgery, it's not going to be pretty," Douglas recalled his doctor saying. The surgery could've resulted in Douglas losing part of his jaw and tongue, so the doctor suggested Douglas misrepresent his type of cancer, and the actor agreed.

The actor also had to deal with his children seeing lurid headlines about his gaunt appearance as he lost weight during seven weeks of radiation and chemotherapy. "I looked pretty weird," Douglas told Jackson. But when he warned Dylan, now 13, that he might face some troubling magazine covers, he found his son was already savvy to the ways of the tabloid press. "You mean like the story when you had three weeks to live, Dad?" Dylan asked.

Douglas also encouraged other men who might be suspicious about a mole, bump or other change that could indicate cancer to get a checkup immediately, rather than wait. "I made that mistake," he said. "I don't want to see you do it."

Douglas has now been cancer-free for two years, and says that doctors tell him this means there's a 95 percent chance his cancer will not return.








Source: http://www.today.com/entertainment/michael-douglas-doctor-told-me-lie-about-my-type-cancer-8C11390754
Similar Articles: Gta 5 Online Not Working   Vma 2013 Miley Cyrus  

Saturday, October 12, 2013

In Theaters This Weekend: Reviews of 'Captain Phillips,' 'Romeo and Juliet' and More


Paul Greengrass' thrilling drama Captain Phillips, starring Tom Hanks, is hitting theaters this weekend after premiering at New York Film Festival last month.



The high-seas biopic, based on events that unfolded in the spring of 2009, follows Hanks as the real-life Captain Richard Phillips who was kidnapped by young Somali pirates while trying to save his crew on the U.S. cargo ship Maersk Alabama. Captain Phillips also stars Somali newcomer Barkhad Abdi as the Somali pirate captain Muse, and Catherine Keener as Phillips' wife, Andrea.


Read what The Hollywood Reporter's film critics have to say about Captain Phillips and other films opening this weekend, and find out how they're expected to perform at the box office.


PHOTOS: On Board With 'Captain Phillips': Exclusive Portraits of Tom Hanks and Barkhad Abdi


Captain Phillips


Paul Greengrass and Tom Hanks team up for a pulsating account of the kidnapping of the captain of an American cargo ship by Somali pirates. Read Todd McCarthy's review here.


Romeo and Juliet


Julian Fellowes adapts a decorous but bland version of the Shakespearean romance, which features Douglas Booth and Hailee Steinfeld. Read Todd McCarthy's review here. 


Sweetwater


January Jones, Jason Isaacs and Ed Harris star in Logan and Noah Miller's Western, based on a story by Andrew McKenzie. Read Todd McCarthy's review here. 


The Inevitable Defeat of Mister & Pete


Jennifer Hudson and Jordin Sparks appear in George Tillman Jr.'s film about two young kids forced to fend for themselves in a tough Brooklyn housing project. Read David Rooney's review here. 


Broadway Idiot


Doug Hamilton's documentary provides an all-access backstage pass to the rock musical "American Idiot," inspired by the Grammy-winning 2004 Green Day album. Read David Rooney's review here. 


Machete Kills


Robert Rodriguez's follow-up to 2010's Machete co-stars Danny Trejo, Michelle Rodriguez, Amber Heard and Mel Gibson and includes an abundance of cameo appearances, including Lady Gaga in her feature debut. Read Justin Lowe's review here. 


STORY: Why Swarovski Crystals Adorn 'Romeo and Juliet's' Costumes


Escape From Tomorrow


Randy Moore’s first feature, about a man who finds out he's been fired from his job while on vacation, was shot surreptitiously at Disney World. Read Todd McCarthy's review here. 


Zero Charisma


A Dungeons & Dragons-obsessed nerd loses the only friends who think he's cool. Read John DeFore's review here. 


God Loves Uganda


Roger Ross Williams’ eye-opening documentary follows evangelicals who travel to Uganda to convert souls and demonize gays. Read James Greenberg's review here. 


I Will Follow You Into The Dark


A woman battles paranormal forces to rescue her missing boyfriend in Mark Edwin Robinson's horror film. Read Frank Scheck's review here. 


Cassadaga


A deaf woman is haunted by the ghost of a serial killer's victim in Anthony DiBlasi's horror film. Read Frank Scheck's review here. 


I Am Divine


Jeffrey Schwarz uncovers the lovable man behind the cross-dressing John Waters muse and pop star. Read John DeFore's review here. 


Source: http://feedproxy.google.com/~r/thr/reviews/film/~3/Fi59ulfWG1w/reviews-captain-phillips-romeo-juliet-647308
Related Topics: First Day Of Fall 2013   What Time Does Ios 7 Come Out   roger federer   taylor swift   The White Queen